10 Mpox Clade 1b Cases Reported in India

India has retrospectively reported ten cases of mpox due to clade Ib mpox virus detected between December 2024 and March 2025.

According to the WHO's Multi-country outbreak of mpox, External situation report #52, as of May 14, 2025, all clade 1b cases reported in India had a recent history of travel to countries in the Gulf or contact with travellers from those countries.

Outside Africa, 16 countries have reported travel-related cases of mpox due to clade Ib: the United Kingdom of Great Britain and Northern Ireland (12 cases), Germany (10 cases), China (seven cases), Belgium (five cases), Qatar (five cases), Thailand (five cases), the United States of America (four cases).

Globally, Cases of mpox due to clade Ib continue to be reported primarily in Africa, where ten countries have reported community transmission of this strain, reaching over 14,000 cases in 2025.

Reported #52 discloses that mpox vaccination in countries in the African Region has more than 668,000 doses of MVA-BN (Bavarian Nordic A/S JYNNEOS®) vaccines administered in seven countries.

From the total number of JYNNEOS doses, 87% have been administered in the Democratic Republic of the Congo.

In the United States, the JYNNEOS vaccine is commercially available at many pharmacies.

The U.S. Food and Drug Administration (FDA) initially approved JYNNEOS for smallpox prevention in September 2019. And on March 31, 2025, the FDA approved the freeze-dried formulation of JYNNEOS.